中醫藥研究論叢

281.6白血病病人治療期間血小板驟降經中醫介入後之療效個案報告

TJ TCM.28(1) : 69-83, 2025

DOI : 10.6516/TJTCM.202503_28(1).0006

白血病病人治療期間血小板驟降經中醫介入後之療效個案報告

A Case Report on the Efficacy of Traditional Chinese Medicine Intervention for Sudden Platelet Decrease During Leukemia Treatment

莊佩蓁1許晉嘉1王瑜婷1,*

1奇美醫學中心永康院區中醫部,台南,台灣

【摘要】
T細胞大顆粒淋巴性白血病(T-LGL leukemia)是罕見的血液腫瘤疾病,在北美地區大概占2-5%的慢性淋巴性增生性疾病(chronic lymphoproliferative disorders),在亞洲大概佔6%。通常在60歲左右發病,男女罹病機率幾乎均等,孩童罕見。主要特徵是血液中大量複製的大顆粒性T細胞或NK cells,可能導致正常血球低下和再生不良性貧血,且與其他自體免疫疾病和淋巴性或骨髓性血液惡性疾病有可能相關。病人可能出現反覆發燒、感染,部分病人有淋巴癌的B symptoms。此66歲女性病人因為手腳多處出血點、輸血頻繁而來到門診就診,經過中醫辨證,採補氣養血、清血熱後,自覺生活品質提升許多,輸血頻率也有下降。
【關鍵詞】白血病 ; 骨髓抑制 ; 血小板低下 ; 歸脾湯 ; 黃連解毒湯
【Summary】
T-cell large granular lymphocyte leukemia (T-LGL leukemia) is a rare hematologic malignancy, acing for approximately 2-5% of chronic lymphoproliferative disorders in North America and around 6% in Asia. Typically diagnosed around the age of 60, this condition affects both genders with almost equal frequency and is rarely observed in children. The distinguishing feature of T-LGL leukemia is the proliferation of large granular T-cells or NK cells in the blood, often resulting in cytopenias and refractory anemia. It is associated with various autoimmune diseases and other lymphoproliferative malignancies. Patients may experience recurrent fever, infections, and occasionally exhibit B symptoms of lymphoma. Here, we present the case of a 66-year-old female patient who sought medical attention due to frequent bleeding episodes and a high demand for blood transfusions. Traditional Chinese Medicine (TCM) intervention was administered based on the principles of tonifying qi, nourishing blood, and clearing heat from the blood. Subsequently, the patient reported a significant improvement in her quality of life, accompanied by a reduced frequency of blood transfusions. This case highlights the potential benefits of TCM as a complementary approach in managing T-LGL leukemia and improving patient outcomes.
【Keywords】Leukemia; Myelosuppresson; Thrombocytopenia; Guipi Decoction; Huanglian Jiedu Decoctionl