The study of pulse occupies an important aspect of traditional Chinese medicine (TCM) in mainly two ways. One concerns the meridian theory and relates to the divination concept of TCM human body because it is one of their main components. Secondly, the study of pulse involves in the determination of position, phenomenon, and corresponding diseases of pulse diagnosis. Most of the literature of pulse study focus on pulse diagnosis and its related technological issues, but only few of them deal with its social and cultural influences. Thus, other than the historical development of pulse study, this study intends to discuss affiliations of pulse study, to explain the position, phenomenon, and of pulse diagnosis, and to uncover the related social and cultural issues.