中醫藥研究論叢

291-4 中醫治療BNT疫苗誘發兒童過敏性皮膚炎病例報告

TJ TCM.29(1) : 51-60, 2026

DOI : 10.6516/TJTCM.202603_29(1).0004

中醫治療BNT疫苗誘發兒童過敏性皮膚炎病例報告

Traditional Chinese Medicine Management of BNT Vaccine-Induced Pediatric Allergic Dermatitis: A Case Report

蘇郁婷1龔彥穎1,2,3陳方佩1,2,3張凱惟1,2,*

1臺北榮民總醫院傳統醫學部,臺北,臺灣

2國立陽明交通大學傳統醫藥研究所,臺北,臺灣

【摘要】
臺灣食品藥物管理署於2022年6月14日核准Moderna COVID-19疫苗與Pfizer-BioNTech COVID-19(輝瑞)兒童劑型疫苗可用於兒童及青少年接種。本病例報告之8歲病童於2022年6月16日接種輝瑞疫苗兒童劑型疫苗後,一周內雙肘窩、雙膝窩陸續出現紅癢疹塊並擴大涉及面部與頸部,紅癢疹塊範圍擴大、顏色變更紅,部分病灶開始出現組織滲液合併糜爛、痂皮、脫屑、苔癬化等多樣皮膚病變。期間曾接受中西醫治療,但效果有限,因而於10月19日至本院接受中藥治療,治則以清熱解毒、化濁利溼為主,方藥使用:甘露消毒丹合消風散加減,治療期間皮膚紅癢疹塊、組織滲液、糜爛等逐漸修復,經中藥治療1個月後,所有病灶皆已痊癒,顯示中醫對於疫苗不良反應有良好的療效,利用中藥藥理對應臨床機轉提高治療效果,減少嚴重度。
【關鍵詞】BNT疫苗 ; 兒童過敏性皮膚炎 ; 甘露消毒丹 ; 消風散
【Summary】
On June 14, 2022, the Taiwan Food and Drug Administration approved the use of the Moderna COVID-19 vaccine and the Pfizer-BioNTech COVID-19 (Pfizer) pediatric vaccine for children and adolescents. An 8-year-old patient in this case report received the Pfizer pediatric vaccine on June 16, 2022. Within a week of receiving the vaccination, the patient developed successive red and itchy rash lesions in the axillae and knee creases, which gradually expanded to involve the face and neck. The extent of the red and itchy rash lesions increased, the color became redder, and some lesions began to exhibit tissue exudation, accompanied by ulceration, crusting, desquamation, and eczematous changes, representing a variety of dermatological manifestations. Starting from October 19, the patient underwent traditional Chinese medicine treatment, focusing on heat-clearing, detoxification, and dampness-eliminating principles. The herbal prescription consisted of Ganlu Xiaodu Dan in combination with Xiao Feng San, with modifications. During the course of treatment, the skin manifestations, tissue exudation, and ulceration gradually improved. After one month of traditional Chinese medicine treatment, all lesions had completely healed, demonstrating the efficacy of traditional Chinese medicine in managing adverse reactions to vaccines. The use of Chinese herbal pharmacology in alignment with clinical mechanisms contributed to enhanced therapeutic effects and reduced severity.
【Keywords】
BNT vaccine ; allergic dermatitis in children ; Ganlu Xiaodu Dan ; Xiao Feng San