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Case Series Analysis and Literature Review of Fuzi Poisoning
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Wei-Chieh Chen1,5¡@Sung-Yuan Hu2¡@Hsiao-Mei Chuang1,5
Shu-Cheng Tseng3¡@Jen-Yu Wang3¡@Hsu-Ming Su3¡@Wei-Huan Lee4
Chia-I Tsai1,4,5¡@Shih-Chang Lee5*
1Department of Traditional Chinese medicine, Taichung Veterans, General Hospital,Taichung, Taiwan
2Division of Clinical Toxicology, Department of Emergency Medicine
3Department of Pharmacy, Taichung Veterans General Hospital, Taichung, Taiwan
4Graduate Institute of Chinese Medicine, College of Chinese Medicine, China Medical University
5School of Chinese Medicine, College of Chinese Medicine, China Medical University
¡iSummary¡j
Fuzi is a Chinese herb widely used in clinical practice. However, fuzi poisoning is not uncommon due to its aconitum alkaloids. There are three cases of fuzi poisoning at Taichung Veterans General Hospital in 2015. Therefore,it is worth further exploring the clinical features and causes of fuzi poisoning.Reviewing domestic and international literature, fuzi poisoning results in presentations of neurological, cardiovascular, and gastrointestinal systems as well as edible mistake, inadequately processing, insufficient decocting times and overdoses are common causes. Tracing the history of three poisoning cases with typical presentations after taking Fuzi 30~90 minutes later, they were caused either by insufficient decocting times or use of inadequately processing of Fuzi. In order to reduce the incidence of Fuzi poisoning, we appeal to the people to follow the instruction of their traditional Chinese physician and pharmacist when taking Fuzi to lower the risks of poisoning.
Keywords¡GAconitine, adverse drug reaction¡]ADR¡^, fuzi poisoning