台北市中醫師公會中醫藥研究論叢

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211.8 吳茱萸湯及其現代藥理與臨床回顧性文獻探微

TJ TCM.21(1) : 85-96, 2018

DOI : 10.6516/TJTCM.201803_21(1).0008

吳茱萸湯及其現代藥理與臨床回顧性文獻探微

Discussion on Wu Zhu Yu Tang and Its Modern Pharmacology with Clinical Literature Reviews

鄭旭廷1　侯秀珍2　曾玉靈2　謝淑鳳1*

1 高雄榮民總醫院傳統醫學科，高雄，台灣

2 高雄榮民總醫院藥學部，高雄，台灣

【摘要】

吳茱萸湯是中醫經典方劑之一，其源自東漢‧張仲景鉅著‧《傷寒雜病論》，歷代醫家均對其有不少研究與論述。本文從歷朝重要本草與醫家著作出發，探討本方的中醫用藥機理與六經定位，再從近代中西醫學論文中，探究其現代用藥機理、毒性作用與臨床使用時機，並統計本院傳統醫學科自2015 年11 月至2017 年06 月間使用本方藥的情形，希望能拓展本方的臨床應用範圍並嘗試找出其臨床治療指引。

【關鍵詞】吳茱萸湯、中西醫用藥機理、臨床應用、吳茱萸鹼

Hsu-Ting Cheng1　Hsiu-Jean Hou2　Yu-Ling Tseng2　Shu-Feng Hsieh1*

1Department of Traditional Chinese Medicine, Kaohsiung Veterans General Hospital,

Kaohsiung, Taiwan

2Department of Pharmacy, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

【Summary】

“Wu Zhu Yu Tang” is one of the classic formulae of Traditional Chinese Medicine, which originated from the masterpiece “Shanghan Zabing Lun” by “Zhang Zhong-jing” (Eastern Han Dynasty). There were lots of research and discussion of this formula from the past history. We review these important works of herbal medicine and those ancient Doctors’ research, trying to realize the mechanism of Chinese medicine and six-meridian positioning of this formula. Besides, we also review many modern articles and research from the medical databases, trying to explore the pharmacological mechanism and toxicity, as well as the timing of clinical use. In addition, we analyze the data of this formula used in our hospital from November 2015 to June 2017, hoping to expand the clinical application of “Wu Zhu Yu Tang” and to find out its clinical guideline.

Keywords：Wu Zhu Yu Tang, mechanism of both chinese and western medicine, clinical application, Evodiamine

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